The Relationship Of Dementia And Diabetes
Hypoglycemia,
a common side effect of diabetes treatment, is associated with high morbidity
and death, and it has become a significant barrier to the delivery of
antidiabetic medication. Severe hypoglycemia, or abnormally low blood sugar, is
linked to seizures and comas, but even mild hypoglycemia can induce
uncomfortable symptoms including anxiety, palpitations, and confusion.Dementia frequently results in the loss of
memory, language, problem solving, and other cognitive abilities that might
interfere with daily activities. There is growing evidence that diabetes is
linked to an increased risk of both vascular and non-vascular dementia.
Neuroglycopenia caused by a hypoglycemia period in diabetic patients can result
in brain cell destruction and cognitive impairment, ultimately leading to
dementia. In light of new evidence, a better understanding of the relationship
between hypoglycemia and dementia may help inform and guide preventive
strategies. This review aims to discuss the epidemiology of dementia in
patients with diabetes and the emerging mechanisms thought to underlie the
relationship between hypoglycemia and dementia
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