Crafting Tomorrow’s Diagnostics: Metal Nanoparticles In Biosensors – Types, Synthesis, And Future Frontiers In Health, Environment, And Food Safety
Anahtar Kelimeler
This
chapter offers an in-depth exploration of the incorporation of metal
nanoparticles (MNPs) into biosensors, showcasing their pivotal role in
revolutionizing diagnostic technologies across a range of sectors, including
healthcare, environmental monitoring, and food safety. The unique
physicochemical properties of MNPs such as their high surface area-to-volume
ratio, distinctive optical and electrical behaviors, and catalytic potential
have made them indispensable in developing highly sensitive and specific
biosensing platforms. The chapter systematically categorizes the various types
of nanomaterials used in biosensors, including gold, silver, palladium,
platinum, copper, nickel, iron oxide, zinc oxide and titanium oxide nanoparticles,
and highlights their applications in critical areas such as real-time disease
detection, pollutant monitoring, and foodborne pathogen identification. It also
delves into the synthesis methods as chemical reduction, green synthesis,
polyol process, sol-gel method, microwave-assisted, laser ablation,
seed-mediated growth, photochemical reduction, electrochemical reduction,
sonochemical reduction, hydrothermal and solvothermal, Moreover, the chapter
examines the technical, regulatory, and commercialization challenges that
hinder the broader adoption of these technologies, particularly in ensuring
reproducibility, stability, and scalability. Looking forward, the chapter
discusses emerging trends, including innovations in point-of-care diagnostics
and the integration of artificial intelligence with biosensor platforms, which
promise to propel the next generation of biosensing technologies. By addressing
these challenges and capitalizing on future opportunities, MNP-based biosensors
have the potential to significantly enhance global public health outcomes,
environmental sustainability, and food safety.
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